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For the permeability determination, refer to review dated. Doxepin HCl qualifies as a highly soluble and highly permeable drug according to the Biopharmaceutics Classification System. The potential applications of BCS in drug discovery, drug delivery and drug research as well as extension for BCS are discussed. The Biopharmaceutics Classification System (BCS) is a scientific framework for classifying drug substances based on their aqueous.
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